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KMID : 0360220180590111077
Journal of the Korean Ophthalmological Society
2018 Volume.59 No. 11 p.1077 ~ p.1081
Two Cases of Corneal Edema Due to Vaporized Amine
Hwang You-Sook

Cho Yang-Kyung
Abstract
Purpose: We report two cases of corneal edema in patients who presented with bilateral blurry vision due to vaporized amines while working in a polyurethane processing plant.

Case summary: A 28?year?old male presented with bilateral blurred vision. His work involved solidifying polyurethane liquid and he often found himself exposed to polyurethane heat and gas. On examination, the patient¡¯s uncorrected visual acuity (UCVA) was 20/40 (right) and 30/50 (left). A slit lamp examination revealed subepithelial microbullae in both eyes. The central corneal thickness (CCT) was also increased in both eyes, measuring 698 ¥ìm (right) and 672 ¥ìm (left). After prescribing 0.5% moxifloxacin and, 1% fluorometholone eye drops for 3 days in both eyes, the UCVA recovered to 20/40 (right) and 20/20 (left). The CCT decreased to 644 ¥ìm (right) and 651 ¥ìm (left), and the microbullae improved significantly in the left eye. The second patient was a 34?year?old female who presented with bilateral decreased visual acuity while at work. She worked in a factory that produced car seat filling. Her UCVA was 20/25 (right) and 20/20 (left). The CCT by specular microscopy was 537 ¥ìm (right) and 541 ¥ìm (left). On slit lamp examination, both eyes demonstrated bilateral central subepithelial edema. The patient did not attend any follow?up outpatient appointments after the initial presentation.

Conclusions: Exposure to vaporized amines such as polyurethane may causereversible corneal toxicityeven without direct contact. Further consideration should be given to ocular safety and protection from amine compounds in the industrial field.
KEYWORD
Corneal edema, Dimethylethylamine, Polyurethane foam, Vapor
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